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Application of ozone sensor in the pharmaceutical industry

by:Rika Sensors     2021-09-16
Application of ozone sensor in the pharmaceutical industry
In pharmaceutical production, GMP regulations have extremely strict requirements on pharmaceutical production (especially sterile products). For this reason, the pharmaceutical production workshop needs to use ozone disinfection to ensure the pharmaceutical production environment. Compared with various traditional disinfection methods, ozone disinfection has a more significant disinfection effect. Ozone can not only effectively kill various bacteria such as Pseudomonas aeruginosa, Escherichia coli and hepatitis virus, but also effectively kill viruses. It can be said that the current ozone disinfection method is The role in pharmaceutical production is becoming more and more important.

Ozone sensors and the pharmaceutical industry

Ozone sensors are mainly used in clean workshops of biopharmaceuticals. Biopharmaceutical workshops generally have relatively high requirements for environmental sanitation, so they not only need to have a good seal, but also need to be thoroughly disinfected. The early disinfection method commonly used in clean workshops of biopharmaceuticals is to disinfect by spraying or fumigating chemicals. However, this method often produces a large amount of fine dust, which has a great impact on the environment of the clean workshop and is implemented. It's also more troublesome. Therefore, with the development of a large number of new disinfection technologies in recent years, clean and hygienic ozone has begun to be widely used in pharmaceutical sterilization, and ozone sensors have therefore been more widely used.

The principle of ozone disinfection

The structure of ozone is unstable under normal temperature and pressure, and it quickly decomposes into oxygen and a single oxygen atom by itself. It has strong activity and has a strong oxidizing effect on bacteria. Ozone oxidizes It decomposes the enzymes necessary for the internal oxidation of the bacteria, thereby destroying its membrane and killing it. The excess oxygen atoms will recombine themselves into ordinary oxygen molecules without any toxic residues, so it is called a pollution-free disinfectant. It is not only It has a strong ability to kill various bacteria (including hepatitis virus, E. coli, Pseudomonas aeruginosa and other bacteria), and it is also very effective in killing molds.

In the 'Disinfection Technical Specifications' promulgated by the Ministry of Health of my country, there are clear regulations on the bactericidal effect, scope and method of use of ozone. It is affirmed that ozone is a broad-spectrum bactericide, which can kill bacterial propagules and spores, viruses, fungi, etc., and can destroy botulinum toxin. The sterilization rate of ozone is faster than that of chlorine.

The working principle of the ozone sensor

1. The principle of electrochemistry

The principle of electrochemistry is mainly to measure the current generated when the target gas enters the sensor and the chemical reaction occurs at the sensing electrode Size, so as to achieve the purpose of detecting its concentration. The electrochemical sensor is actually a fuel cell component composed of a sensing electrode and a negative electrode, which requires no maintenance and is stable for a long time. Not only that, the ozone sensor of urban technology has high resolution, fast response speed, and has technical support personnel to provide users with application guidance services.

2. Semiconductor

Semiconductor ozone sensors use gas-sensitive semiconductor materials, such as WO3, Sn0, In203 and other pieces of oxide made of sensitive elements, when they absorb ozone, redox reactions occur, produce or release The heat causes the temperature of the component to change accordingly, so that the resistance changes, the concentration of ozone is converted into an electrical signal, and the ozone concentration is measured. Generally, as the lifted concentration increases, the resistance of the component increases significantly, within a certain range Within, the relationship is linear.

3. The principle of ultraviolet light

The ozone gas analyzer adopts the principle of ultraviolet absorption. It uses a stable ultraviolet light source to generate ultraviolet light. The light wave filter filters out other wavelength ultraviolet light, and only allows 253.7nm ultraviolet light to pass through. After the sample photoelectric sensor, it is absorbed by ozone to reach the sampling photoelectric sensor. By comparing the electrical signals of the sample photoelectric sensor and the sampling photoelectric sensor, the mathematical model calculation is carried out according to the Lambert-Beer law to obtain the ozone concentration.

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